Searchable abstracts of presentations at key conferences in endocrinology

ea0032p747 | Obesity | ECE2013

Short-term ovariectomy did not cause tissues proinflammatory state, but associated with hyperlipidic diet caused hyperleptinemia and increased body weight gain

de Sousa Rodrigues Maria Elizabeth , Neto Nelson Inacio Pinto , Oyama Lila Missae , Okuda Marcos Hiromu , Hachul Ana Claudia , Santos Bruno dos , Moreno Mayara , do Nascimento Claudia Oller

Obesity leads to low-grade inflammation, and high-fat diet is one of the major causes. On the other hand, menopause can aggravate it by promoting food intake alterations, and metabolic and endocrine adaptations. Thus, we used ovariectomized rats fed with high-fat diet to evaluate changes on the tissue inflammatory state. Forty days-old female Wistar rats were fed with: a hyperlipidic diet enriched with lard – H-group; or chow diet – C-group; for 30 days. After this p...